Endoventricular porcine autologous myoblast transplantation can be successfully achieved with minor mechanical cell damage
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چکیده
منابع مشابه
Autologous skeletal myoblast transplantation for severe postinfarction left ventricular dysfunction.
OBJECTIVES This phase I trial was designed to assess the feasibility and safety of autologous skeletal myoblast transplantation in patients with severe ischemic cardiomyopathy. BACKGROUND Experimentally, myoblast grafting into postinfarction myocardial scars improves left ventricular function. METHODS Ten patients were included on the basis of the following criteria: 1) severe left ventricu...
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Articular cartilage is known to have poor healing capacity after injury. Autologous chondral grafting remains the mainstay to treat well-defined, full-thickness, symptomatic cartilage defects. We demonstrated the utilization of gelatin microbeads to deliver autologous chondrocytes for in vivo cartilage generation. Chondrocytes were harvested from the left forelimbs of 12 Lee-Sung pigs. The cell...
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Duchenne Muscular Dystrophy (DMD) is an inherited muscle disease that is characterized by a lack of dystrophin expression in the membrane cytoskeleton of muscle fibers. This lack of dystrophin is responsible for muscle fiber necrosis which leads to the muscle atrophy and progressive muscle weakness, characteristic of the DMD pathology. Myoblast transplantation and gene therapy based on viral ve...
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متن کاملStorage-induced damage to red blood cell mechanical properties can be only partially reversed by rejuvenation.
BACKGROUND The storage of red blood cells (RBC) is associated with impairment of their properties that can induce a circulatory risk to recipients. In a preceding study (2009), we reported that post-storage rejuvenation (RJ) of stored RBC (St-RBC) efficiently reduced the storage-induced RBC/endothelial cell interaction, while only partially reversing the level of intracellular Ca(2+), reactive ...
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ژورنال
عنوان ژورنال: Cardiovascular Research
سال: 2003
ISSN: 0008-6363
DOI: 10.1016/s0008-6363(02)00834-9